Prions Archives - Home Health Beauty Tips https://homehealthbeauty.in/tag/prions/ Homemade Health and Beauty Tips Tue, 02 Dec 2014 10:03:13 +0000 en-US hourly 1 https://wordpress.org/?v=6.3.4 https://homehealthbeauty.in/wp-content/uploads/favicon-1.png Prions Archives - Home Health Beauty Tips https://homehealthbeauty.in/tag/prions/ 32 32 Liposomes can be used to deliver Drugs for Cancer https://homehealthbeauty.in/health/liposomes-can-be-used-to-deliver-drugs-for-cancer/ https://homehealthbeauty.in/health/liposomes-can-be-used-to-deliver-drugs-for-cancer/#respond Sun, 07 Dec 2014 00:01:27 +0000 http://homehealthbeauty.in/?p=923 Article Body: A liposome is a small vesicle, made out of the similar material as a cell membrane. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. These are bilayer, liquid-filled bubbles made from phospholipids. These can be used to summarize powerfully hydrophilic molecules solved in aqueous solutions, such as clodronate, a […]

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A liposome is a small vesicle, made out of the similar material as a cell membrane. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. These are bilayer, liquid-filled bubbles made from phospholipids. These can be used to summarize powerfully hydrophilic molecules solved in aqueous solutions, such as clodronate, a non-toxic biophosphonate, developed for human application. Their size generally ranges from 50 nm to several micrometers.

Drugs for Cancer

Drugs for Cancer

These are generally classified by their structure:
Unilamellar liposomes: Spherical concentric unilamellar structures
Multilamellar liposomes: Spherically concentric multilamellar structures
These can be composed of obviously-copied phospholipids with mixed lipid chains, or of pure surfactant modules like DOPE. These are colloidal systems which are used in a broad range of industries including the pharmaceutical and customer product divisions.
The properties of liposomes as well as the common properties of surfactants those make them helpful for different applications are:
Changing permeability of the bilayer to different molecules
Ability to trick both water soluble and insoluble materials and deliver them into desired environments
Structural constancy on dilution
These are biocompatible so they have been used in medicine as carriers of drugs.  The inside of a liposome can be crowded with medication, vaccines, DNA, and a diversity of other substances.

Biocompatible

Biocompatible

A prion is an infectious agent that is composed chiefly of protein. Prions are proteins that are unique in their ability to replicate on their own and become infectious. These are unprecedented infectious pathogens that cause a group of habitually deadly neurodegenerative diseases by a completely novel mechanism. These are transmissible particles that are devoid of nucleic acid and appear to be composed wholly of a customized protein. These are conjectured to contaminate and spread by refolding unusually into a structure which is able to change usual molecules of the protein into the abnormally structured form.
These diseases are all caused by the breakdown of the nervous system, which is willingly obvious after autopsy or necropsy. These found in animals completely infect the brain, are fatal and terminal.  All known these persuade the formation of an amyloid fold, in which the protein polymerises into an aggregate consisting of firmly packed beta sheets. Providentially, they appear to lie chiefly in nervous system tissue, although overwhelming meat from an animal with TSE could potentially be hazardous. It has been planned that normal PrP can become misfolded in disease in such a manner that it provides a guide or template for the refolding of neighbouring normal PrP.

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